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SFA cancer research lab focuses attention on giant salvinia

Dr. Shiyou Li is research professor and director of the Center for Pharmaceutical Crops at Stephen F. Austin State University.
Stephen F. Austin State University
Dr. Shiyou Li is research professor and director of the Center for Pharmaceutical Crops at Stephen F. Austin State University.

This winter’s hard freezes are helpful in fighting the spread of the invasive aquatic weed giant salvinia that continues to choke area waterways. 

Dr. Shiyou Li is research professor and director of the Center for Pharmaceutical Crops at Stephen F. Austin State University.
Credit Stephen F. Austin State University
Dr. Shiyou Li is research professor and director of the Center for Pharmaceutical Crops at Stephen F. Austin State University.

Researchers at Stephen F. Austin State University are working on a new control. Turns out, a compound found in the plant could be lethal to itself. That compound was discovered in an SFA pharmaceutical research lab that investigates anti-cancer agents found in native and invasive plants, according to Steve Bullard, dean of SFA’s Arthur Temple College of Forestry and Agriculture.

"In a way we considersalviniato be an environmental cancer. The approach to dealing with it, just like in human cancer we work with chemotherapy and radiation, we’re thinking that multiple approaches are needed for this," Bullard said.

The director of SFA’s National Center for Pharmaceutical Crops, Shiyou Li, and his colleagues have isolated more than 50 compounds in giant salvinia. One of them shows promising bioactivities against human pancreatic and lung cancer cells. And yet another compound in the plant is toxic to itself. Li calls it an endogenous biocide or "endocide" for short.

“Some chemicals in certain plants may have a poison function on their own, so we introduced a new term called endogenous biocide," Li said.

SFA recently signed a cooperative endeavor agreement with the Red River Waterway Commission to work on field trials in central Louisiana. Li has completed three years of extensive research in his lab at SFA and has successfully controlled giant salvinia in various stages of growth.

Now, he wants to replicate his findings on test ponds. He’s also pursuing a patent on his work and seeking broader clearance from the Environmental Protection Agency to test the endocides on salvinia-infested waters.

Copyright 2021 Red River Radio. To see more, visit Red River Radio.

Chuck Smith
Chuck Smith brings more than 30 years' experience to Red River Radio having started out as a radio news reporter and moving into television journalism as a newsmagazine producer / host, talk-show moderator, programming director and managing producer and news director / anchor for commercial, public broadcasting and educational television. He has more recently worked in advertising, marketing and public relations as a writer, video producer and media consultant. In pursuit of higher learning, Chuck studied Mass Communications at Southern Arkansas University in Magnolia and motion picture / television production at the University of California at Los Angeles. He has also taught writing for television at York Technical College in Rock Hill, South Carolina and video / film production at Centenary College of Louisiana, Shreveport.

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