Louisiana officials are investigating a Union Pacific train derailment about 60 miles west of Baton Rouge. About 100 homes have been evacuated.
The 26-car train derailed Sunday. The track was inspected about three hours before the accident. An engineer and a conductor were on board but they were not hurt.
One of the cars began leaking sodium hydroxide, which can be fatal if inhaled or touched. Another was leaking lube oil. State police say those leaks are contained.
Louisiana Governor Bobby Jindal toured the scene. He says a damage assessment is under way.
The tracks are expected to be closed for at least two days.